Milligan, S. R.Mirembe, Florence M.2022-01-232022-01-231984Milligan, S. R., & Mirembe, F. M. (1984). Time course of the changes in uterine vascular permeability associated with the development of the decidual cell reaction in ovariectomized steroid-treated rats. Reproduction, 70(1), 1-6.https://rep.bioscientifica.com/view/journals/rep/70/1/jrf_70_1_001.xmlhttps://nru.uncst.go.ug/xmlui/handle/123456789/1447Uterine vascular permeability and tissue blood volume during the development of the oil-induced decidual cell reaction (DCR) in ovariectomized steroid\x=req-\ treated rats were assessed by measuring the extravascular accumulation of 125I-labelled human serum albumin and the tissue content of 51 Cr-labelled red cells 30 min after intravenous administration. Within 15 min of oil instillation into one uterine horn, the vascular permeability of the horn was significantly elevated. Permeability rose to a sharp peak (10 times control levels) 9 h after oil instillation, but dropped to 5 times control values by 12 h and continued a steady decline over the next 7 days. Although a marked increase in uterine weight was associated with the development of the DCR, there was no significant change in blood volume/g tissue until 4 days after oil instillation.enTime courseUterine vascularDecidual cell reactionOvariectomized steroid-treated ratsArticle