Asige, ElizabethSaloojee, GillianAndrews, CarinNamaganda, Lukia HKakooza‐Mwesige, AngelinaDamiano, Diane LForssberg, Hans2025-01-092025-01-092025-01Asige, Elizabeth, Gillian Saloojee, Carin Andrews, et al. 'Functioning and Activity Outcomes of the Akwenda Intervention Program for Children and Young Adults with Cerebral Palsy in Uganda: A cluster‐randomized Trial', Developmental Medicine and Child Neurology, vol. 67/no. 1, (2025), pp. 87-98.ISSN 0012-1622, 1469-8749EISSN 1469-8749https://nru.uncst.go.ug/handle/123456789/9739Aim To evaluate the efficacy of the Akwenda Intervention Program on motor, self-care, and social function of children and young people with cerebral palsy (CP). Method This was a cluster-randomized, controlled, single-blinded, intervention study of 100 participants with CP (2–23 years; 52 males) in rural eastern Uganda. Half were allocated to the intervention program, the remainder served as waitlist controls. Gross Motor Function Measure-66 (GMFM-66) and the Ugandan version of Pediatric Evaluation of Disability Inventory (PEDI-UG) were collected before group allocation and after intervention. General linear models and t -tests were used to compare changes within and between groups. Cohen's d estimated the effect size of group differences. Change scores were evaluated by age and mobility subgroups. Results Significant group by time interactions were found for GMFM-66 ( p  =0.003) and PEDI-UG outcomes ( p  <0.001), except mobility, with the intervention group demonstrating greater changes. Both groups increased their scores on the GMFM-66 and child PEDI-UG, while only the intervention group had significant increases in caregiver assistance scores and across all age and mobility subgroups. Cohen's d showed large effect sizes ( d  >0.8) of differences for PEDI-UG outcomes except mobility. Interpretation The Akwenda Intervention Program had a large positive impact on functioning and activity across age and mobility levels.enArticle