Najjuka, Sarah MariaCheckwech, GaudenciaOlum, RonaldAshaba, ScholasticKaggwa, Mark Mohan2022-06-162022-06-162021Najjuka, S. M., Checkwech, G., Olum, R., Ashaba, S., & Kaggwa, M. M. (2021). Depression, anxiety, and stress among Ugandan university students during the COVID-19 lockdown: an online survey. African Health Sciences, 21(4), 1533-43.https://dx.doi.org/10.4314/ahs.v21i4.61680-6905https://nru.uncst.go.ug/handle/123456789/3986COVID19 pandemic forced most countries to lockdown, leading to the prolonged closure of many learning institutions. This dramatic shift led to increase of mental illness symptoms among university students.To determine the prevalence and factors associated with symptoms of depression, anxiety, and stress among Uganda’s university students during the COVID-19 lockdown.We conducted a one-month online survey using the Depression Anxiety and Stress Scale (DASS-21).Participants n=321 were enrolled with mean age, 24.8(SD=5.1) years and 198(61.7%) were males. The prevalence of mental health symptoms among participants was 80.7%, 98.4%, and 77.9% for depression, high levels of anxiety, and stress, respectively. Statistically significant association between mental health symptoms on multi-logistic regression was found with Males (depression=2.97[1.61–5.48] and stress=1.90[1.07–3.35]), engagement in leisure activity (depression= 1.87[1.01–3.49] and stress=1.98[1.10–3.56]), and being finalist (stress=0.55[0.31– 0.97]). Use of addictive substances seem to potentially alleviate symptoms of depression, anxiety and stress in the short term. The findings of this study suggest a high prevalence of symptoms of depression, anxiety and stress among university students during the COVID-19 lockdown. Students’ mental health should be monitored by all stakeholders, especially as the pandemic progresses.enCOVID-19 lockdown; University students; Mental health.Article