Okwi, Andrew LivexOcaido, MichaelByarugaba, WilsonMagala Ndugwa, ChristopherParkes, Arthur2021-12-132021-12-132009Okwi, A. L., Ocaido, M., & Byarugaba, W. (2009). Solubility tests and the peripheral blood film method for screening for sickle-cell disease: A cost benefit analysis. South African Medical Journal, 99(12).https://www.ajol.info/index.php/samj/article/view/50880https://nru.uncst.go.ug/xmlui/handle/123456789/438To determine the cost benefit of screening for sicklecell disease among infants at district health centres in Uganda using sickling, solubility tests and the peripheral blood film method. Methods. Pilot screening services were established at district health centres. Cost benefit analysis (CBA) was performed in four scenarios: A1 – where there are no sickle-cell screening services at district health centres and all children are referred either to Mulago national referral hospital or A2 – a regional hospital for haemoglobin (Hb) electrophoresis; B1 – when there are screening services at district health centres, only positive samples are taken either to Mulago Hospital or B2 – the regional hospital for confirmation using haemoglobin electrophoresis. Calculations were done in Uganda shillings (USh).enPeripheral blood film methodScreeningSickle-cell diseasArticle