Stöhr, WolfgangFidler, SarahMcClure, MyraWeber, JonathanCooper, DavidRamjee, GitaKaleebu, PontianoTambussi, GiuseppeSchechter, MauroBabiker, AbdelPhillips, Rodney E.Porter, KholoudFrater, John2022-01-052022-01-052013Stöhr W, Fidler S, McClure M, Weber J, Cooper D, et al. (2013) Duration of HIV-1 Viral Suppression on Cessation of Antiretroviral Therapy in Primary Infection Correlates with Time on Therapy. PLoS ONE 8(10): e78287. doi:10.1371/journal.pone.007828710.1371/journal.pone.0078287https://nru.uncst.go.ug/xmlui/handle/123456789/1087A minority of HIV-1 positive individuals treated with antiretroviral therapy (ART) in primary HIV-1 infection (PHI) maintain viral suppression on stopping. Whether this is related to ART duration has not been explored. Design: And Methods: Using SPARTAC trial data from individuals recruited within 6 months of seroconversion, we present an observational analysis investigating whether duration of ART was associated with post-treatment viraemic control. Kaplan-Meier estimates, logistic regression and Cox models were used. 165 participants reached plasma viral loads (VL) 12 weeks compared to ≤12 weeks (p=0.061). Cumulative probabilities of remaining 12 weeks. In multivariable regression, ART for >12 weeks was independently associated with a lower probability of being ≥400 copies/ml within 12 weeks of ART stop (OR=0.11 (95%CI=0.03,0.34), penHIV-1 Viral SuppressionAntiretroviral TherapyPrimary InfectionArticle