Makumbi, Fredrick E.Ssempijja, VictorSekasanvu, JosephSsekubugu, RobertKigozi, GodfreyWatya, StephenNakigozi, GertrudeSerwadda, DavidWawer, MariaGray, Ronald H.2022-03-112022-03-112016Makumbi, F. E., Ssempijja, V., Sekasanvu, J., Ssekubugu, R., Kigozi, G., Watya, S., ... & Gray, R. H. (2016). Postcoital penile washing and the risk of HIV acquisition in uncircumcised men. AIDS, 30(10), 1669-1673. DOI:10.1097/QAD.00000000000010970269-937010.1097/QAD.0000000000001097https://nru.uncst.go.ug/xmlui/handle/123456789/2681Postcoital genital washing by uncircumcised men may affect the risk of male HIV acquisition. Method: We assessed the association between self-reported washing after sex in 2976 initially HIV-negative, uncircumcised men enrolled in a prospective cohort study in Rakai, Uganda. Results: Data from the 2976 participants who reported sexual intercourse in the past 12 months contributed 4290 visits, with 7316.6 person-years of observation during the 2-year follow-up. The overall HIV-incidence was 1.28/100 person-years 95%CI (1.04–1.57). About 91.0% of men reported washing their penis after sex, and their HIV incidence was 1.34/100 person-years (95%CI 1.08–1.66), compared with an incidence of 0.62/100 person-years (95%CI 0.17–1.60) in men who did not wash their penis after intercourse. Using Poisson multivariable regression, the adjusted incidence rate ratio of HIV acquisition associated with postcoital washing was 1.94 (95%CI 0.71–5.29). Conclusion: Postcoital penile washing, as practiced in this rural African population does not afford protection from HIV acquisition among uncircumcised men, and may increase risk.enHIV incidencePostcoital washingRakaiUgandaUncircumcised menArticle