McDowell, DanielHurt, LisaStothard, John RussellLello, JoanneKabatereine, Narcis B2023-01-252023-01-252022-03-05McDowell, Daniel, Lisa Hurt, Narcis B. Kabatereine, et al. 'Infection History and Current Coinfection with Schistosoma Mansoni Decreases Plasmodium Species Intensities in Preschool Children in Uganda', The Journal of Infectious Diseases, vol. 225/no. 12, (2022), pp. 2181-2186.0022-18991537-6613 (Online)https://nru.uncst.go.ug/handle/123456789/7195Abstract Malaria–schistosomiasis coinfections are common in sub-Saharan Africa but studies present equivocal results regarding the interspecific relationships between these parasites. Through mixed-model analyses of a dataset of Ugandan preschool children, we explore how current coinfection and prior infection with either Schistosoma mansoni or Plasmodium species alter subsequent Plasmodium intensity, Plasmodium risk, and S mansoni risk. Coinfection and prior infections with S mansoni were associated with reduced Plasmodium intensity, moderated by prior Plasmodium infections, wealth, and host age. Future work should assess whether these interactions impact host health and parasite control efficacy in this vulnerable age group.enCoinfection, Schistosoma mansoni, Plasmodium species, preschool-aged children, prior infectionsArticle