Rwai Waweru, WilsonObado Osuwat, LawrenceWambui Mureithi, Connie2023-03-052023-03-052017Waweru, W. R., Osuwat, L. O., & Mureithi, C. W. (2017). Analgesic and anti-Inflammatory activity of Tradescantia fluminensis leaves extract. The Journal of Phytopharmacology2320-480Xhttps://nru.uncst.go.ug/handle/123456789/8074The present study sought to evaluate the anti-inflammatory and analgesic activities of ethanolic extract from Tradescantia fluminensis leaves. Methods: The crude leaf extract of T. fluminensis was investigated for anti-inflammatory and analgesic activities in Wistar Albino rats and mice respectively. The anti-inflammatory activity was investigated using egg albumin induced oedema model while acetic acid and formalin-induced paw licking models were used to evaluate the analgesic activity. Results: The extract showed a significant (P<0.05) dose-dependent inhibition of inflammation and pain compared to the control group. Conclusion: The leaf extract possesses anti-inflammatory and analgesic activities. The activities could be attributed to phytochemicals present in the plant.enTradescantia fluminensisAnalgesic activityAnti-inflammatory activityArticle