Habteyes, Abrham TesfayeMekuria, Mihret DebebeNegeri, Haweni AdugnaKassa, Roza TeshomeDeribe, Leul KitawSendo, Endalew Gemechu2024-07-052024-07-052024-07Habteyes, Abrham Tesfaye, Mihret Debebe Mekuria, Haweni Adugna Negeri, et al. 'Prevalence and Associated Factors of Caesarean Section among Mothers Who Gave Birth Across Eastern Africa Countries: Systematic Review and Meta-Analysis Study', Heliyon, vol. 10/no. 12, (2024), pp. e32511.ISSN 2405-8440EISSN 2405-8440https://nru.uncst.go.ug/handle/123456789/9592Background: Caesarean section (CS) rate increased dramatically worldwide, exceeding the World Health Organization's benchmark (10–15 %) in many countries. This rate varies in different regions of the continent. Using various study designs, researchers from across East African countries investigated the prevalence of caesarean section and the factor associated with it but no study shows a pooled prevalence of caesarean section in the Eastern African region. Therefore, this review aimed to systematically summarize and estimate the pooled prevalence of caesarean section and its associated factors in Eastern Africa, 2023. Methods: PubMed, Web of Science, EMBASE, Scopus and CINAHL were rigorously searched to find relevant studies. All identified observational studies reporting the prevalence of CS and its associated factors in East Africa published till August 2023 were considered. Heterogeneity across the studies was evaluated using the I2 test. Publication bias was assessed by funnel plot and Egger's regression test. Finally, a random effect meta-analysis model was computed to estimate the pooled prevalence of CS and qualitative analysis was employed for associated factors. The study protocol was registered in PROSPERO. Results: This review was assessed using twenty-six eligible studies from a total of 2223 articles with a total of 600,431 participants. In this meta-analysis, the pooled prevalence of caesarean section in Eastern Africa was 24.0 % (95%CI: 22–27 %). The highest pooled prevalence of caesarean section was in Ethiopia, 28.30 % (95%CI; 21.3–35.2 %), and the lowest was seen in Uganda, 11.9 % (95%CI; 7.9–15.9 %). Urban residency, having high level of wealth asset, education level college and above, advanced maternal age, big birth weight, history of previous caesarean section, private institution delivery, multiple pregnancies, pregnancy-induced hypertension, antepartum haemorrhage and fetal malpresentation were linked with a greater likelihood of having CS. Conclusions: and recommendation: The overall pooled prevalence of CS in Eastern Africa was high compared to the WHO proposed recommended range. Therefore, the finding implies that each East African countries Ministry of Health and health care professionals shall be given particular emphasis made on strengthening antenatal care services and ensure more women have access to skilled healthcare professionals during childbirth. This can help in providing appropriate interventions, support to women and reducing the need for emergency and unnecessary CSs. The result of this research are a baseline data for future researchers to conduct further studies to better understand the reasons behind the high rates and identify potential interventions and solutions specific to the African context.PROSPERO protocol number: CRD42023440131.enArticle