Chamie, GabrielCharlebois, Edwin D.Walusimbi-Nanteza, MariaMugerwa, Roy D.Mayanja, HarrietOkwera, AlphonseWhalen, Christopher C.Havlir, Diane V.2023-03-062023-03-062010Chamie, G., Charlebois, E. D., Srikantiah, P., Walusimbi-Nanteza, M., Mugerwa, R. D., Mayanja, H., ... & Havlir, D. V. (2010). Mycobacterium tuberculosis microbiologic and clinical treatment outcomes in a randomized trial of immediate versus CD4+-initiated antiretroviral therapy in HIV-infected adults with a high CD4+ cell count. Clinical infectious diseases, 51(3), 359-362.https://doi.org/10.1086/6547991537-6591https://nru.uncst.go.ug/handle/123456789/8082In a prospective randomized, controlled trial in Uganda comparing the efficacy of antiretroviral therapy during tuberculosis therapy with the efficacy of tuberculosis therapy alone in HIV-infected patients with tuberculosis who have a CD4+ cell count >350 cells/µL, it was found that antiretroviral therapy did not accelerate microbiologic, radiographic, or clinical responses to tuberculosis therapy: 18% of participants had sputum smears positive for Mycobacterium tuberculosis after 5 months of tuberculosis therapy, despite having had negative culture results.enMycobacterium tuberculosis MicrobiologicHigh CD4+ Cell CountHIV-Infected AdultsClinical Treatment OutcomesTechnical Report