Byakika‑Kibwika, PaulineNyakato, PatienceLamorde, MohammedKiragga, Agnes N.2022-01-122022-01-122018Byakika-Kibwika, P., Nyakato, P., Lamorde, M., & Kiragga, A. N. (2018). Assessment of parasite clearance following treatment of severe malaria with intravenous artesunate in Ugandan children enrolled in a randomized controlled clinical trial. Malaria journal, 17(1), 1-6. https://doi.org/10.1186/s12936-018-2552-6https://doi.org/10.1186/s12936-018-2552-6https://nru.uncst.go.ug/xmlui/handle/123456789/1204Worldwide, malaria ranks as one of the most important causes of morbidity and mortality with 216 million cases and 445,000 deaths in 2016 alone, 90% of cases and deaths occur in Africa and 80% in sub-Saharan Africa Uganda is one of the heavy malaria burden countries where Plasmodium falciparum, which causes the most severe form of disease is the most prevalent [1]. Malaria is transmitted by the female Anopheles mosquito which injects sporozoites into the human host. Sporozoites undergo pre-erythrocytic and erythrocytic stages of multiplication causing erythrocyte rupture with release of merozoites and pro-inflammatory cytokines into circulation, which are responsible for the symptoms. Patients seek medical attention when they begin to experience symptoms of malaria.enArtesunateACTMalariaParasite clearanceArticle