Gupta, MadhuWahl, BrianAdhikari, BinitaBar-Zeev, NaorBhandari, SudipCoria, AlexandraErchick, Daniel J.Gupta, NidhiHariyani, ShreyaKagucia, Wangeci E.Killewo, JaphetJayant Limaye, RupaliMcCollum, Eric D.Pandey, RaghukulPomat, William S.Rao, Krishna D.Santosham, MathuramSauer, MollyWanyenze, Rhoda K.Peters, David H.2021-12-112021-12-112020Gupta, M., Wahl, B., Adhikari, B., Bar-Zeev, N., Bhandari, S., Coria, A., ... & Peters, D. H. (2020). The need for COVID-19 research in low-and middle-income countries. Global Health Research and Policy, 5(1), 1-4.https://link.springer.com/article/10.1186/s41256-020-00159-yhttps://nru.uncst.go.ug/xmlui/handle/123456789/332In the early months of the pandemic, most reported cases and deaths due to COVID-19 occurred in high-income countries. However, insufficient testing could have led to an underestimation of true infections in many low- and middle-income countries. As confirmed cases increase, the ultimate impact of the pandemic on individuals and communities in low- and middle-income countries is uncertain. We therefore propose research in three broad areas as urgently needed to inform responses in low- and middle-income countries: transmission patterns of SARS-CoV-2, the clinical characteristics of the disease, and the impact of pandemic prevention and response measures. Answering these questions will require a multidisciplinary approach led by local investigators and in some cases additional resources. Targeted research activities should be done to help mitigate the potential burden of COVID-19 in low- and middle-income countries without diverting the limited human resources, funding, or medical supplies from response activities.enCOVID-19Research agendaGlobal healthArticle