Seremba, E.Ssempijja, V.Kalibbala, S.Gray, R. H.Wawer, M. J.Nalugoda, F.Casper, C.Phipps, W.Ocama, P.Serwadda, D.Thomas, D. L.Reynolds, S. J.2022-01-202022-01-202017Seremba, E., Ssempijja, V., Kalibbala, S., Gray, R. H., Wawer, M. J., Nalugoda, F., ... & Reynolds, S. J. (2017). Hepatitis B incidence and prevention with antiretroviral therapy among HIV positive individuals in Rakai, Uganda. AIDS (London, England), 31(6), 781. doi:10.1097/QAD.0000000000001399.10.1097/QAD.0000000000001399.https://nru.uncst.go.ug/xmlui/handle/123456789/1365Antiretroviral therapy (ART) may interfere with replication of hepatitis B (HBV) raising the hypothesis that HBV infection might be prevented by ART. We investigated the incidence and risk factors associated with HBV among HIV-infected adults in Rakai, Uganda. Methods—We screened stored sera from 944 HIV-infected adults enrolled in the Rakai Community Cohort Study between September 2003 and March 2015 for evidence of HBV exposure. Serum from participants who tested anti-HBc negative (497) at baseline were tested over 3-7 consecutive survey rounds for incident HBV. Poisson incidence methods were used to estimate incidence of HBV with 95% confidence intervals while Cox proportional regression methods were used to estimate hazard ratios.enHepatitis BAntiretroviral therapyHIV positive individualsRakaiUgandaArticle