Ssuuna, CharlesGaliwango, Ronald MosesKankaka, Edward NelsonKagaayi, JosephNdyanabo, AnthonyKigozi, GodfreyNakigozi, GertrudeLutalo, TomSsekubugu, RobertWasswa, John BoscoMayinja, AnthonyNakibuuka, Martina CathyJamiru, SamiriOketch, John BaptistMuwanga, EdwardChang, Larry WilliamGrabowski, Mary KateWawer, MariaGray, RonaldAnderson, MarkSerwadda, David2021-12-182021-12-182021Ssuuna, C., Galiwango, RM, Kankaka, EN, Kagaayi, J., Ndyanabo, A., Kigozi, G., ... & Serwadda, D. (2021). Severe Acute Respiratory Syndrome Coronavirus-2 Seropositivity in South-Central Uganda, During 2019–2021. Research square . https://doi.org/10.21203/rs.3.rs-960585/v1https://doi.org/10.21203/rs.3.rs-960585/v1https://nru.uncst.go.ug/xmlui/handle/123456789/783Globally, key subpopulations such as healthcare workers (HCWs) have a higher risk of contracting SARS-CoV-2. In Uganda, limited access to personal protective equipment amidst lack of clarity on the extent and pattern of the community disease burden may exacerbate this situation. We assessed SARS-CoV-2 antibody seroprevalence among high-risk sub-populations in South-central Uganda, including HCWs, persons within the general population previously reporting experiencing key COVID-19 like symptoms (fever, cough, loss of taste and smell) and archived plasma specimens collected between October 2019 – 18th March 2020, prior to confirmation of COVID-19 in Uganda.enSARS-CoV-2 seroprevalenceHealthcare workersCOVID-19South-central UgandaArticle