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dc.contributor.authorLogie, Carmen
dc.contributor.authorOkumu, Moses
dc.contributor.authorHakiza, Robert
dc.contributor.authorKibuuka Musoke, Daniel
dc.contributor.authorBerry, Isha
dc.contributor.authorMwima, Simon
dc.contributor.authorKyambadde, Peter
dc.contributor.authorMimy Kiera, Uwase
dc.contributor.authorLoutet, Miranda
dc.contributor.authorNeema, Stella
dc.contributor.authorNewby, Katie
dc.contributor.authorMcNamee, Clara
dc.contributor.authorBaral, Stefan D.
dc.contributor.authorLester, Richard
dc.contributor.authorMusinguzi, Joshua
dc.contributor.authorMbuagbaw, Lawrence
dc.date.accessioned2022-04-29T11:51:04Z
dc.date.available2022-04-29T11:51:04Z
dc.date.issued2021
dc.identifier.citationLogie, C., Okumu, M., Hakiza, R., Musoke, D. K., Berry, I., Mwima, S., ... & Mbuagbaw, L. (2021). Mobile health–Supported HIV self-testing strategy among urban refugee and displaced youth in Kampala, Uganda: Protocol for a cluster randomized trial (Tushirikiane, Supporting Each Other). JMIR research protocols, 10(2), e26192. doi: 10.2196/26192en_US
dc.identifier.other10.2196/26192
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/2959
dc.description.abstractHIV is the leading cause of mortality among youth in sub-Saharan Africa. Uganda hosts over 1.43 million refugees, and more than 83,000 live in Kampala, largely in informal settlements. There is limited information about HIV testing uptake and preferences among urban refugee and displaced youth. HIV self-testing is a promising method for increasing testing uptake. Further, mobile health (mHealth) interventions have been effective in increasing HIV testing uptake and could be particularly useful among youth. Objective: This study aims to evaluate the feasibility and effectiveness of two HIV self-testing implementation strategies (HIV self-testing intervention alone and HIV self-testing combined with an mHealth intervention) in comparison with the HIV testing standard of care in terms of HIV testing outcomes among refugee/displaced youth aged 16 to 24 years in Kampala, Uganda. Methods: A three-arm cluster randomized controlled trial will be implemented across five informal settlements grouped into three sites, based on proximity, and randomization will be performed with a 1:1:1 method. Approximately 450 adolescents (150 per cluster) will be enrolled and followed for 12 months. Data will be collected at the following three time points: baseline enrollment, 8 months after enrollment, and 12 months after enrollment. Primary outcomes (HIV testing frequency, HIV status knowledge, linkage to confirmatory testing, and linkage to HIV care) and secondary outcomes (depression, condom use efficacy, consistent condom use, sexual relationship power, HIV stigma, and adolescent sexual and reproductive health stigma) will be evaluated. Results: The study has been conducted in accordance with CONSORT (Consolidated Standards of Reporting Trials) guidelines. The study has received ethical approval from the University of Toronto (June 14, 2019), Mildmay Uganda (November 11, 2019), and the Uganda National Council for Science and Technology (August 3, 2020). The Tushirikiane trial launched in February 2020, recruiting a total of 452 participants. Data collection was paused for 8 months due to COVID-19. Data collection for wave 2 resumed in November 2020, and as of December 10, 2020, a total of 295 participants have been followed-up. The third, and final, wave of data collection will be conducted between February and March 2021. Conclusions: This study will contribute to the knowledge of differentiated HIV testing implementation strategies for urban refugee and displaced youth living in informal settlements. We will share the findings in peer-reviewed manuscripts and conference presentations.en_US
dc.language.isoenen_US
dc.publisherJMIR research protocolsen_US
dc.subjectAdolescents and youthen_US
dc.subjectImplementation researchen_US
dc.subjectHIV testingen_US
dc.subjectMobile healthen_US
dc.subjectRefugeeen_US
dc.subjectUgandaen_US
dc.titleMobile Health–Supported HIV Self-Testing Strategy Among Urban Refugee and Displaced Youth in Kampala, Uganda: Protocol for a Cluster Randomized Trial (Tushirikiane, Supporting Each Otheren_US
dc.typeArticleen_US


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