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dc.contributor.authorNazziwa, Rose
dc.contributor.authorMwesige, Angelina Kakooza
dc.contributor.authorObua, Celestino
dc.contributor.authorSsenkusu, John M.
dc.contributor.authorMworozi, Edison
dc.date.accessioned2022-02-28T12:56:47Z
dc.date.available2022-02-28T12:56:47Z
dc.date.issued2014
dc.identifier.citationNazziwa, R., Mwesige, A. K., Obua, C., Ssenkusu, J. M., & Mworozi, E. (2014). Adherence to antiepileptic drugs among children attending a tertiary health unit in a low resource setting. Pan African Medical Journal, 17(1).https://doi.org/10.11604/pamj.2014.17.44.3399en_US
dc.identifier.issn1937-8688
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/2323
dc.description.abstractEpilepsy is one of the neglected and highly stigmatised diseases, yet it is very common affecting about 70 million people worldwide. In Uganda, the estimated prevalence of epilepsy is 13% with about 156 new cases per 100,000 people per year. Adherence to antiepileptic drugs is crucial in achieving seizure control yet in Uganda; there is lack of information on adherence to antiepileptic drugs and the factors that affect this among children. This study was therefore designed to determine the level of adherence to antiepileptic drugs and the factors that are associated with non adherence. Methods: In a cross sectional study, 122 children who met the inclusion criteria were enrolled and interviewed using a pretested questionnaire. Assessment of adherence to antiepileptic drugs was done by self report and assay of serum drug levels of the antiepileptic drugs. Focus group discussions were held to further evaluate the factors that affect adherence. Results: Age range was 6 months - 16 years, male to female ratio 1.3:1 and majority had generalised seizures 76 (62.3%). Adherence to antiepileptic drugs by self report was 79.5% and 22.1% by drug levels. Majority of the children in both adherent and non adherent groups by self report had inadequate drug doses (95/122).Children were found to be more non-adherent if the caregiver had an occupation (p-value 0.030, 95%CI 1.18-28.78) Majority of children had good adherence levels when estimated by self report. The caregiver having an occupation was found to increase the likelihood of non adherence in a child.en_US
dc.language.isoenen_US
dc.publisherPan African Medical Journalen_US
dc.subjectAdherence, antiepileptic drugs, children, Epilepsy, Low resource settingen_US
dc.titleAdherence to Antiepileptic Drugs among Children Attending a Tertiary Health Unit in a Low Resource Setting.en_US
dc.typeArticleen_US


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