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Detection of K103N in Ugandan women after repeated exposure to single dose Nevirapine

Flysa, Tamara S.; Mwathab, Anthony; Guay, Laura A.; Nakabiitoc, Clemensia; Donnell, Deborah; Musoke, Philippa; Mmirod, Francis; Jacksona, J. Brooks; Eshleman, Susan H. (Journal of virology, 2007)

Objectives: Use of single dose nevirapine (SD NVP) for prevention of HIV-1 mother-tochild transmission (pMTCT) is associated with selection of K103N-containing HIV variants. Repeat use of SD NVP for pMTCT may influence ...

Association of cord blood Nevirapine concentration with reported timing of dose and HIV-1 transmission

Jackson, J. Brooks; Parsons, Teresa; Musoke, Philippa; Nakabiito, Clemensia; Donnell, Deborah; Fleming, Thomas; Mirochnick, Mark; Mofenson, Lynne; Fowler, Mary Glenn; Mmiro, Francis; Guay, Laura (Aids, 2006)

Background: To correlate nevirapine presence and concentration in cord bloods of infants born to HIV-1 infected women with report of timing of dose and HIV-1 transmission at 6 weeks of age. Methods: All available cord ...