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dc.contributor.authorChan, Brian T.
dc.contributor.authorWeiser, Sheri D.
dc.contributor.authorBoum, Yap
dc.contributor.authorHaberer, Jessica E.
dc.contributor.authorKembabazi, Annet
dc.contributor.authorHunt, Peter W.
dc.contributor.authorMartin, Jeffrey N.
dc.contributor.authorMocello, A. Rain
dc.contributor.authorBangsberg, David R.
dc.contributor.authorTsai, Alexander C.
dc.date.accessioned2022-01-31T11:46:09Z
dc.date.available2022-01-31T11:46:09Z
dc.date.issued2015
dc.identifier.citationChan, B. T., Weiser, S. D., Boum, Y., Haberer, J. E., Kembabazi, A., Hunt, P. W., ... & Tsai, A. C. (2015). Declining prevalence of probable depression among patients presenting for antiretroviral therapy in rural Uganda: The role of early treatment initiation. AIDS and Behavior, 19(1), 19-26. DOI 10.1007/s10461-014-0785-0en_US
dc.identifier.other10.1007/s10461-014-0785-0
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1666
dc.description.abstractLittle is known about trends in depression at antiretroviral therapy (ART) initiation among people living with HIV (PLHIV) in low- and middle-income countries. We used data from an ongoing cohort of treatment -naı¨ve PLHIV in rural Uganda to estimate secular trends in depression among PLHIV at ART initiation. We fitted linear regression models with depression symptom severity as the outcome variable and year of cohort entry (2005–2012) as the explanatory variable, adjusting for socio-demographic variables and assessing physical health score, body mass index (BMI), and CD4 count as potential mediators of a secular trend in depression symptom severity. There was a statistically significant negative association between year of entry and depression symptom severity, suggesting a 3.1 % relative decline in the mean depression symptom severity score at ART initiation in each year of study recruitment after the first year. This trend remained statistically significant after inclusion of baseline socio demographic characteristics to the model and appeared to be driven by improved physical health scores, but not CD4 count or BMI.en_US
dc.language.isoenen_US
dc.publisherAIDS and Behavioren_US
dc.subjectDepressionen_US
dc.subjectTrendsen_US
dc.subjectPhysical healthen_US
dc.subjectAntiretroviral therapyen_US
dc.subjectHIVen_US
dc.subjectUgandaen_US
dc.titleDeclining Prevalence of Probable Depression Among Patients Presenting for Antiretroviral Therapy in Rural Uganda: The Role of Early Treatment Initiationen_US
dc.typeArticleen_US


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