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Effectiveness of WHO’s pragmatic screening algorithm for child contacts of tuberculosis cases in resource-constrained settings: a prospective cohort study in Uganda
(Lancet Respir Med, 2017)
Background Tuberculosis is a leading cause of global childhood mortality; however, interventions to detect undiagnosed tuberculosis in children are underused. Child contact tracing has been widely recommended but poorly ...
Contact Investigation for Active Tuberculosis Among Child Contacts in Uganda
(Oxford University Press, 2013)
Background. Tuberculosis is a large source of morbidity and mortality among children. However, limited studies characterize childhood tuberculosis disease, and contact investigation is rarely implemented in high-burden ...
Emphasizing the vitality of genomics related research in the area of infectious diseases
(Scientific Research and Essays, 2007)
Sequencing of the human and other species genomes has generated a downstream of sciences that have taken advantage of this knowledge to generate vital links between diseases and genetic variants. Sub-Saharan Africa and ...
Tuberculosis and human immunodeficiency virus co-infections and their predictors at a hospital-based HIV/AIDS clinic in Uganda
(The International journal of tuberculosis and lung disease, 2010)
To evaluate the burden of TB-HIV (tuberculosis-human immunodeficiency virus) co-infections and their predictors in an urban hospital-based HIV programme. DESIGN: Prospective observational study. METHODS: Clinicians screened ...
Effectiveness of the standard WHO recommended retreatment regimen (Category II) for tuberculosis in Kampala, Uganda
(PLoS medicine, 2011)
Each year, 10%–20% of patients with tuberculosis (TB) in low- and middle-income countries present with
previously treated TB and are empirically started on a World Health Organization (WHO)-recommended standardized
retreatment ...
Methanolic extracts of Aloe secundiflora Engl. inhibits in vitro growth of tuberculosis and diarrhea-causing bacteria
(Phcog Res, 2011)
The emergence of resistance to antimicrobials by pathogens has reached crisis levels, calling for identification of alternative means to combat diseases. Objective: To determine antimicrobial activity of crude methanolic ...
Diagnostic accuracy of the Cepheid 3-gene host response fingerstick blood test in a prospective, multi-site study: interim results
(Clinical Infectious Diseases, 2021)
The development of a fast and accurate, non-sputum-based point-of-care triage test for tuberculosis (TB) would have a major impact on combating the TB burden worldwide. A new fingerstick blood test has been developed by ...
Heritability Analysis of Cytokines as Intermediate Phenotypes of Tuberculosis
(The Journal of infectious diseases, 2003)
Numerous studies have provided support for genetic susceptibility to tuberculosis (TB); however, heterogeneity
in disease expression has hampered previous genetic studies. The purpose of this work was to investigate
possible ...
Burden of tuberculosis in Kampala, Uganda
(World Health Organization, 2003)
Over the past two decades, the number of tuberculosis cases has risen worldwide, especially in the developing countries of southeast Asia and sub-Saharan Africa, where co-infection with human immunodeficiency virus (HIV) ...
Prevalence, risk factors and treatment outcomes of isoniazid resistant TB in Bulawayo city, Zimbabwe: A cohort study
(The Journal of Infection in Developing Countries, 2020)
The isoniazid-resistant TB poses a threat to TB control efforts. Zimbabwe, one of the high TB burden countries, has not explored the burden of isoniazid resistant TB. Hence among all bacteriologically-confirmed TB patients ...